pentobarbital will lessen the level or result of methylprednisolone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.

Sodium valproate and valproic acid appear to reduce barbiturate metabolism; for that reason, barbiturate blood concentrations should be monitored and proper dosage adjustments manufactured as indicated.

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pentobarbital will lower the extent or outcome of fesoterodine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.

pentobarbital will lessen the level or influence of estradiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.

pentobarbital will reduce the extent or impact of eltrombopag by influencing hepatic enzyme CYP2C9/10 metabolism. Use Caution/Monitor.

pentobarbital will lessen the level or outcome of buspirone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.

MAOI lengthen the effects of barbiturates likely for the reason that metabolism in the barbiturate is inhibited.

pentobarbital will reduce the level or impact of etravirine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.

pentobarbital will decrease the extent or outcome of ramelteon by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Importance Unfamiliar.

pentobarbital will minimize the extent or influence of tamoxifen by impacting hepatic enzyme CYP2C9/ten metabolism. Use Caution/Keep track of.

pentobarbital will lower the extent or effect of duvelisib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Coadministration with a powerful CYP3A inducer decreases duvelisib area beneath the curve (AUC), which can minimize duvelisib efficacy.

pentobarbital will lessen the extent or impact of lapatinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.

pentobarbital will lessen the more info extent or impact of suvorexant by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor. Robust CYP3A4 inducers may well decrease suvorexant efficacy; if elevated suvorexant dose essential, never exceed 20 mg/day